Cyclosporin A ：In stock Cyclosporin A powder with 99% safe shipping to you Cas: 59865-13-3

Chemical Name: Cyclosporin A

CAS Number: 59865-13-3

Molecular Formula: C62H111N11O12

Molecular Weight: 1202.6 g/mol

Appearance: White to off-white crystalline powder

Solubility: Slightly soluble in water, soluble in alcohol and chloroform

Storage Conditions: Store in a cool, dry place, away from light and moisture.

What is Cyclosporin A?
Cyclosporin A is an immunosuppressant initially extracted from a fungus in soil. It is primarily used to prevent organ rejection after transplantation and to treat autoimmune diseases like rheumatoid arthritis and psoriasis. It works by inhibiting T-cell activation, thus suppressing the immune response and preventing the immune system from attacking the body’s normal tissues.

Action and Applications of Cyclosporin A

Immunosuppression
Cyclosporin A is a potent immunosuppressant widely used after organ transplants to prevent rejection. By inhibiting T-cell activity, it reduces the immune system's attack on transplanted organs, thus improving transplant success rates.

Treatment of Autoimmune Diseases
Cyclosporin A is also used to treat immune-mediated diseases such as rheumatoid arthritis, psoriasis, and lupus. By reducing excessive immune reactions, it helps alleviate inflammation and improve patients' quality of life.

Anti-inflammatory Action
Cyclosporin A plays a role in treating certain inflammatory diseases, particularly chronic inflammation caused by immune system abnormalities. It effectively inhibits excessive immune cell reactions and alleviates inflammation symptoms.

Topical Use
In ophthalmology, Cyclosporin A is used to treat dry eye syndrome by reducing inflammation and improving tear secretion.

Induction of Immune Tolerance
Cyclosporin A has also been used in some studies to induce immune tolerance, helping suppress immune reactions to certain substances or cells, providing a foundation for novel treatment approaches.

Safety and Side Effects
The use of Cyclosporin A should be under the supervision of a qualified healthcare professional. Due to its strong immunosuppressive effect, it may increase the risk of infection and, with long-term use, may lead to kidney dysfunction, hypertension, and other side effects. Regular monitoring of kidney function, blood pressure, and other physiological indicators is required during treatment.

Summary
Cyclosporin A is an important immunosuppressive drug widely used in organ transplantation, treatment of autoimmune diseases, and local inflammation. By inhibiting T-cell function, it reduces immune system overreaction, prevents rejection, and alleviates autoimmune conditions. Despite its significant efficacy, it comes with potential side effects, so its use requires strict dosage control and monitoring.