Aprotinin：Bulk price for Aprotinin Protease Inhibitor powder with good quality Cas: 9087-70-1

Chemical Name: Aprotinin

CAS Number: 9087-70-1

Molecular Formula: C58H80N6O9S2

Molecular Weight: Approximately 651.5 g/mol

Appearance: White to off-white powder

Solubility: Soluble in water

Storage Conditions: Store in a cool, dry place at 2-8°C, protected from light and moisture.

What is Aprotinin?
Aprotinin is a naturally occurring protein inhibitor, classified as a protease inhibitor. It works by inhibiting the activity of a range of proteases, and it is widely used in medical applications.

Action and Applications of Aprotinin

Medical Applications
Aprotinin is primarily used to reduce bleeding during surgery, especially in cardiac surgery and liver transplantation. It inhibits proteases in the blood, reducing the formation of blood clots and thereby lowering blood loss. In heart surgery, it is commonly used to reduce inflammatory responses and other complications associated with cardiopulmonary bypass.

Anti-inflammatory Effects
When used as an anti-inflammatory agent, Aprotinin helps alleviate inflammatory reactions, especially in cases of inflammation following major surgeries or trauma. It works by inhibiting specific proteases (such as trypsin and chymotrypsin), reducing tissue damage.

Cancer Research
In some cancer treatment studies, Aprotinin has shown potential in inhibiting tumor growth. By inhibiting enzymes associated with cancer cell proliferation and metastasis, it may provide adjunctive support in the treatment of certain cancers.

Agricultural Use
Aprotinin is also used in agriculture as a natural antimicrobial agent to prevent the spread of plant diseases. It inhibits certain protease activities in plants, slowing the proliferation of pathogenic microorganisms.

Safety and Side Effects
Although Aprotinin is a potent anti-inflammatory and protease inhibitor, it may cause allergic reactions, particularly when used long-term or at high doses. Common side effects include allergic reactions, hypotension, nausea, and vomiting. Close monitoring of patient responses is required, especially in sensitive populations.

Summary
Aprotinin is an important protease inhibitor used widely in the medical field, particularly in cardiac surgery and trauma treatment. By inhibiting protease activity, it helps reduce bleeding and inflammation. Careful attention to dosage and potential allergic reactions is needed to ensure safe and effective treatment outcomes.