β-ESTRADIOL Estradiol ：Safe shipping β-ESTRADIOL Estradiol powder with good price Cas: 50-28-2

Chemical Name: β-estradiol

CAS Number: 50-28-2

Molecular Formula: C18H24O2

Molecular Weight: 272.39 g/mol

Appearance: Colorless crystalline

Solubility: Soluble in ethanol, ether, and chloroform; slightly soluble in water

Storage Conditions: Store in a cool, dry place, protected from light and moisture.

What is β-ESTRADIOL?

β-estradiol (Estradiol) is one of the most important estrogens in the human body, classified as a steroid hormone. It is primarily secreted by the ovaries, placenta, and to a lesser extent, the adrenal glands. Estradiol is also present in men but at lower concentrations. It plays a key role in female physiological processes, including promoting the development of sexual characteristics, regulating the menstrual cycle, and providing protective effects on the bones, cardiovascular system, and nervous system.

Actions and Applications of β-ESTRADIOL

Regulation of the Menstrual Cycle:

Estradiol plays a critical role in the female menstrual cycle, helping to regulate ovarian function and promoting the growth of the endometrium, preparing the uterus for pregnancy. Its levels fluctuate during the different phases of the menstrual cycle, influencing follicular maturation and ovulation.

Development of Female Sexual Characteristics:

During puberty, estradiol promotes the development of female sexual characteristics, such as breast development, widening of the pelvis, and the distribution of body fat. These physiological changes are key indicators of female maturation.

Bone Health Protection:

Estradiol has significant protective effects on bone health. It helps maintain bone density by promoting mineralization and reducing bone resorption, thus playing a potential role in preventing osteoporosis and fractures in the elderly.

Cardiovascular Health:

Estradiol contributes to cardiovascular health by promoting vasodilation, lowering blood pressure, and improving cholesterol levels, which helps protect the blood vessels. A lack of estradiol is associated with an increased risk of cardiovascular diseases.

Neuroprotective Effects:

Estradiol also plays an important role in the nervous system, influencing neurotransmitter release and brain function, providing neuroprotective effects. Research indicates that estradiol may help alleviate symptoms of neurodegenerative diseases, such as Alzheimer's disease.

Hormone Replacement Therapy:

Estradiol is widely used in hormone replacement therapy (HRT) to treat symptoms associated with decreased estrogen levels, such as hot flashes and insomnia during menopause. It is also used in gender-affirming treatment to help transgender women develop female sexual characteristics.

Safety and Side Effects

As a hormone-based medication, estradiol should be used with caution. Long-term excessive use of estradiol may increase the risk of breast cancer, uterine cancer, and blood clots. Therefore, estradiol use should be guided by a physician, especially in elderly women and patients with high-risk diseases.

Summary

β-estradiol (Estradiol) is an essential female hormone that plays a significant role in female physiological health, the development of sexual characteristics, and the protection of bones, cardiovascular, and nervous systems. It is widely used for treating menopausal symptoms and hormone replacement therapy, but care must be taken regarding its side effects.